NOD2 and TLR2 signal via TBK1 and PI31 to direct cross-presentation and CD8 T cell responses
NOD2 and TLR2 recognize components of bacterial cell wall peptidoglycan and direct defense against enteric pathogens. CD8+ T cells are important for immunity to such pathogens but how NOD2 and TLR2 induce antigen specific CD8+ T cell responses is unknown. Here, we define how these pattern recognitio...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Journal article |
| Published: |
Frontiers Media
2019
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