Iridium-catalyzed C4-alkylation of 2,6-di-tert-butylphenol by using hydrogen-borrowing catalysis

Iridium-catalyzed C4-alkylation of 2,6-di-tert-butylphenol by using hydrogen-borrowing catalysis

An iridium-catalyzed hydrogen borrowing process has been developed whereby 2,6-di-tert-butylphenol can be alkylated at the C4-position using a range of different primary alcohols (11 examples, 40–93% yield). Following this, a selection of the products obtained underwent retr...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Frost, J, Cheong, C, Donohoe, T
Fformat:	Journal article
Cyhoeddwyd:	Thieme 2016

Eitemau Tebyg

A vinyl cyclopropane ring expansion and iridium‐catalyzed hydrogen borrowing cascade
gan: Wübbolt, S, et al.
Cyhoeddwyd: (2020)

A vinyl cyclopropane ring expansion and iridium‐catalyzed hydrogen borrowing cascade
gan: Wubbolt, S, et al.
Cyhoeddwyd: (2020)

Hydrogen-Borrowing and Interrupted-Hydrogen-Borrowing Reactions of Ketones and Methanol Catalyzed by Iridium.
gan: Shen, D, et al.
Cyhoeddwyd: (2014)

Hydrogen-borrowing and interrupted-hydrogen-borrowing reactions of ketones and methanol catalyzed by iridium
gan: Shen, D, et al.
Cyhoeddwyd: (2015)

The iridium-catalysed alkylation of aromatic ketones via hydrogen borrowing
gan: Cheong, C
Cyhoeddwyd: (2018)

Cyclometalated Iridium Complex-Catalyzed N‑Alkylation of Amines with Alcohols via Borrowing Hydrogen in Aqueous Media
gan: NianHua Luo, et al.
Cyhoeddwyd: (2020-10-01)

Enantioconvergent alkylation of ketones with racemic secondary alcohols via hydrogen borrowing catalysis
gan: Cheang, DMJ, et al.
Cyhoeddwyd: (2020)

Antioxidative Activity of Ferrocenes Bearing 2,6-Di-Tert-Butylphenol Moieties
gan: E. R. Milaeva, et al.
Cyhoeddwyd: (2010-01-01)

The α-alkylation of ketones using hydrogen borrowing catalysis
gan: Akhtar, W
Cyhoeddwyd: (2018)

The Structure of 2,6-Di-<i>tert</i>-butylphenol–Argon by Rotational Spectroscopy
gan: Wenqin Li, et al.
Cyhoeddwyd: (2023-12-01)

Functional group tolerant hydrogen borrowing C-alkylation
gan: Bailey, EP, et al.
Cyhoeddwyd: (2024)

Functional group tolerant hydrogen borrowing C-alkylation
gan: Bailey, EP, et al.
Cyhoeddwyd: (2024)

Functional group tolerant hydrogen borrowing C-alkylation
gan: Elliot P. Bailey, et al.
Cyhoeddwyd: (2024-06-01)

Hydrogen borrowing catalysis with secondary alcohols: a new route for the generation of β-branched carbonyl compounds
gan: Akhtar, W, et al.
Cyhoeddwyd: (2017)

Strategic application and transformation of ortho-disubstituted phenyl and cyclopropyl ketones to expand the scope of hydrogen borrowing catalysis.
gan: Frost, J, et al.
Cyhoeddwyd: (2015)

Recent developments in transition metal-catalyzed asymmetric borrowing hydrogen catalysis
gan: Nidhi Garg, et al.
Cyhoeddwyd: (2023-12-01)

Hydrogen borrowing catalysis using 1° and 2° alcohols: investigation and scope leading to α and β branched products
gan: Frost, JR, et al.
Cyhoeddwyd: (2021)

Extension of hydrogen borrowing alkylation reactions for the total synthesis of (–)-γ-lycorane
gan: Hall, C, et al.
Cyhoeddwyd: (2022)

Crystal stucture of 4-((10H-phenothiazin-10-yl)methyl)-2,6-di-tert-butylphenol, C27H31NOS
gan: Wang Limin, et al.
Cyhoeddwyd: (2017-07-01)

Ligand‐Promoted [Pd]‐Catalyzed α‐Alkylation of Ketones through a Borrowing‐Hydrogen Approach
gan: Dr. Seetharaman Manojveer, et al.
Cyhoeddwyd: (2023-01-01)

Control of absolute stereochemistry in transition-metal-catalyzed hydrogen borrowing reactions
gan: Kwok, T, et al.
Cyhoeddwyd: (2020)

tert-Butylphenolic Derivatives from Paenibacillus odorifer—A Case of Bioconversion
gan: Thi-Bach-Le Nguyen, et al.
Cyhoeddwyd: (2018-08-01)

Hydrogen-Borrowing Alkylation of 1,2-Amino Alcohols in the Synthesis of Enantioenriched γ-Aminobutyric Acids
gan: Hall, CJJ, et al.
Cyhoeddwyd: (2021)

Catalytic activity of CuI/CuII cyanide based phenanthroline-bicarbonate system for enhancing aerobic oxidation of 2,6-di-tert-butylphenol
gan: S. El-khalafy, et al.
Cyhoeddwyd: (2022-05-01)

Natural Sources and Bioactivities of 2,4-Di-Tert-Butylphenol and Its Analogs
gan: Fuqiang Zhao, et al.
Cyhoeddwyd: (2020-01-01)

Controlling absolute stereochemistry in hydrogen borrowing catalysed alkylation
gan: Cheang, DMJ-Y
Cyhoeddwyd: (2023)

Dynamic kinetic resolution allows control of remote stereochemistry in asymmetric hydrogen borrowing alkylation
gan: Cheang, DMJ, et al.
Cyhoeddwyd: (2025)

Stereoselective synthesis of cyclohexanes via an iridium catalyzed (5 + 1) annulation strategy
gan: Akhtar, WM, et al.
Cyhoeddwyd: (2018)

Iridium(I)-Catalyzed Isoindolinone-Directed Branched-Selective Aromatic C–H Alkylation with Simple Alkenes
gan: Maoqian Xiong, et al.
Cyhoeddwyd: (2022-03-01)

Homogeneous Metastable Hexagonal Phase Iridium Enhances Hydrogen Evolution Catalysis
gan: Shize Geng, et al.
Cyhoeddwyd: (2023-04-01)

Iridium-catalyzed direct asymmetric reductive amination utilizing primary alkyl amines as the N-sources
gan: Zitong Wu, et al.
Cyhoeddwyd: (2022-06-01)

Efficacy of 2,4-Di-tert-butylphenol in Reducing Ralstonia solanacearum Virulence: Insights into the Underlying Mechanisms
gan: Le Yang, et al.
Cyhoeddwyd: (2024-01-01)

Stereoselective synthesis of alicyclic ketones: a hydrogen borrowing approach
gan: Armstrong, RJ, et al.
Cyhoeddwyd: (2019)

Recent Progress in Iridium-Catalyzed Enantioselective Hydrogenation: Tetrasubstituted Olefins and Polyenes
gan: Marcus G. Schrems, et al.
Cyhoeddwyd: (2008-06-01)

Metal-ligand cooperative iridium complex catalyzed C-alkylation of oxindole and 1,3-dimethylbarbituric acid using alcohols
gan: Ao Song, et al.
Cyhoeddwyd: (2023-08-01)

Synthesis of tert-amylbenzene for side-chain alkylation of cumene catalyzed by a solid superbase
gan: Zhou Xin, et al.
Cyhoeddwyd: (2021-12-01)

Nickel-catalyzed allylic carbonylative coupling of alkyl zinc reagents with tert-butyl isocyanide
gan: Yangyang Weng, et al.
Cyhoeddwyd: (2020-01-01)

Alkyl dehydrogenation in iridium tri-cyclopentyl phosphines
gan: Moret, S, et al.
Cyhoeddwyd: (2010)

Alkyl dehydrogenation in iridium tri-cyclopentyl phosphines
gan: Moret, S, et al.
Cyhoeddwyd: (2010)

Hydrogen borrowing-based methods for the construction of quaternary stereocentres
gan: Crompton, J, et al.
Cyhoeddwyd: (2025)