CD8+ T cells specific for conserved, cross-reactive Gag epitopes with strong ability to suppress HIV-1 replication

Background: Development of AIDS vaccines for effective prevention of circulating HIV-1 is required, but no trial has demonstrated definitive effects on the prevention. Several recent T-cell vaccine trials showed no protection against HIV-1 acquisition although the vaccines induced HIV-1-specific T-c...

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Bibliographic Details
Main Authors: Murakoshi, H, Zou, C, Kuse, N, Akahoshi, T, Chikata, T, Gatanaga, H, Oka, S, Hanke, T, Takiguchi, M
Format: Journal article
Language:English
Published: BioMed Central 2018