Prolyl hydroxylase domain enzyme 2 is the major player in regulating hypoxic responses in rheumatoid arthritis.

OBJECTIVE: Rheumatoid arthritis (RA) is characterized by hypoxia and the expression of hypoxia-inducible transcription factors (HIFs), which coordinate cellular responses to hypoxia. The objective of this study was to analyze the expression and regulation of prolyl hydroxylase domain (PHD) enzymes...

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Bibliographic Details
Main Authors: Muz, B, Larsen, H, Madden, L, Kiriakidis, S, Paleolog, E
Format: Journal article
Language:English
Published: 2012