Prolyl hydroxylase domain enzyme 2 is the major player in regulating hypoxic responses in rheumatoid arthritis.

OBJECTIVE: Rheumatoid arthritis (RA) is characterized by hypoxia and the expression of hypoxia-inducible transcription factors (HIFs), which coordinate cellular responses to hypoxia. The objective of this study was to analyze the expression and regulation of prolyl hydroxylase domain (PHD) enzymes...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Muz, B, Larsen, H, Madden, L, Kiriakidis, S, Paleolog, E
Format: Journal article
Sprache:English
Veröffentlicht: 2012