P511 In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs

Safety and efficacy of antiarrhythmic drugs are still a great challenge in cardiology. Drug-induced EP changes in both Purkinje and ventricular cardiomyocytes have been implicated in arrhythmogenesis in vivo, and can be investigated through human-based computer models.

Bibliographic Details
Main Authors: Trovato, C, Passini, E, Tissier, A, Nagy, N, Varro', A, Severi, S, Rodriguez, B
Format: Journal article
Published: Oxford University Press 2017