P511 In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs
Safety and efficacy of antiarrhythmic drugs are still a great challenge in cardiology. Drug-induced EP changes in both Purkinje and ventricular cardiomyocytes have been implicated in arrhythmogenesis in vivo, and can be investigated through human-based computer models.
| Main Authors: | , , , , , , |
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| Format: | Journal article |
| Published: |
Oxford University Press
2017
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| _version_ | 1797097275576549376 |
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| author | Trovato, C Passini, E Tissier, A Nagy, N Varro', A Severi, S Rodriguez, B |
| author_facet | Trovato, C Passini, E Tissier, A Nagy, N Varro', A Severi, S Rodriguez, B |
| author_sort | Trovato, C |
| collection | OXFORD |
| description | Safety and efficacy of antiarrhythmic drugs are still a great challenge in cardiology. Drug-induced EP changes in both Purkinje and ventricular cardiomyocytes have been implicated in arrhythmogenesis in vivo, and can be investigated through human-based computer models. |
| first_indexed | 2024-03-07T04:53:11Z |
| format | Journal article |
| id | oxford-uuid:d5b05d93-2167-4769-9a01-1b4bc53fea9d |
| institution | University of Oxford |
| last_indexed | 2024-03-07T04:53:11Z |
| publishDate | 2017 |
| publisher | Oxford University Press |
| record_format | dspace |
| spelling | oxford-uuid:d5b05d93-2167-4769-9a01-1b4bc53fea9d2022-03-27T08:27:45ZP511 In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d5b05d93-2167-4769-9a01-1b4bc53fea9dSymplectic Elements at OxfordOxford University Press2017Trovato, CPassini, ETissier, ANagy, NVarro', ASeveri, SRodriguez, BSafety and efficacy of antiarrhythmic drugs are still a great challenge in cardiology. Drug-induced EP changes in both Purkinje and ventricular cardiomyocytes have been implicated in arrhythmogenesis in vivo, and can be investigated through human-based computer models. |
| spellingShingle | Trovato, C Passini, E Tissier, A Nagy, N Varro', A Severi, S Rodriguez, B P511 In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs |
| title | P511 In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs |
| title_full | P511 In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs |
| title_fullStr | P511 In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs |
| title_full_unstemmed | P511 In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs |
| title_short | P511 In silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs |
| title_sort | p511 in silico trials in human ventricular and purkinje cell models predict safety and efficacy of 10 antiarrhythmic drugs |
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