Syntheses of derivatives of L-daunosamine and its C-3 epimer employing as the key step the asymmetric conjugate addition of a homochiral lithium amide to tert-butyl (E,E)-hexa-2,4-dienoate
The highly diastereoselective asymmetric conjugate addition of lithium (-4-A'-benzyl-a-methylbenzylamide to methyl or /ert-butyl (£,£)-hexa-2,4-dienoate, followed by osmium tetroxide-catalysed dihydroxylation of the resulting adducts, provides a concise route to methyl L-daunosaminide hydrochlo...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1999
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