Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms.

MicroRNAs are important regulators of gene expression, yet the functional outputs of most microRNA-target interactions remain elusive. Here we introduce the Drosophila melanogaster microRNA sponge (miR-SP) as a powerful transgenic technology to dissect the function of every microRNA with precise spa...

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Bibliographic Details
Main Authors: Loya, C, Lu, C, Van Vactor, D, Fulga, T
Format: Journal article
Language:English
Published: 2009