Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms.
MicroRNAs are important regulators of gene expression, yet the functional outputs of most microRNA-target interactions remain elusive. Here we introduce the Drosophila melanogaster microRNA sponge (miR-SP) as a powerful transgenic technology to dissect the function of every microRNA with precise spa...
Autori principali: | Loya, C, Lu, C, Van Vactor, D, Fulga, T |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2009
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