Transgenic microRNA inhibition with spatiotemporal specificity in intact organisms.
MicroRNAs are important regulators of gene expression, yet the functional outputs of most microRNA-target interactions remain elusive. Here we introduce the Drosophila melanogaster microRNA sponge (miR-SP) as a powerful transgenic technology to dissect the function of every microRNA with precise spa...
Главные авторы: | Loya, C, Lu, C, Van Vactor, D, Fulga, T |
---|---|
Формат: | Journal article |
Язык: | English |
Опубликовано: |
2009
|
Схожие документы
-
A genome-wide transgenic resource for conditional expression of Drosophila microRNAs.
по: Bejarano, F, и др.
Опубликовано: (2012) -
MicroRNA-276a functions in ellipsoid body and mushroom body neurons for naive and conditioned olfactory avoidance in Drosophila.
по: Li, W, и др.
Опубликовано: (2013) -
Understanding neuronal connectivity through the post-transcriptional toolkit.
по: Loya, C, и др.
Опубликовано: (2010) -
Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau.
по: Santa-Maria, I, и др.
Опубликовано: (2015) -
MicroRNA Profiling of Transgenic Mice with Myocardial Overexpression of Nucleolin
по: Qing-Lan Lyu, и др.
Опубликовано: (2018-01-01)