Indolyne experimental and computational studies: synthetic applications and origins of selectivities of nucleophilic additions.

Efficient syntheses of 4,5-, 5,6-, and 6,7-indolyne precursors beginning from commercially available hydroxyindole derivatives are reported. The synthetic routes are versatile and allow access to indolyne precursors that remain unsubstituted on the pyrrole ring. Indolynes can be generated under mild...

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Bibliographic Details
Main Authors: Im, G, Bronner, S, Goetz, A, Paton, R, Cheong, P, Houk, K, Garg, N
Format: Journal article
Language:English
Published: 2010