Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.

CONTEXT: Recent studies have shown an association between cigarettes per day (CPD) and a nonsynonymous single-nucleotide polymorphism in CHRNA5, rs16969968. OBJECTIVE: To determine whether the association between rs16969968 and smoking is modified by age at onset of regular smoking. DATA SOURCES: Pr...

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Detalles Bibliográficos
Autores principales: Hartz, S, Short, SE, Saccone, N, Culverhouse, R, Chen, L, Schwantes-An, T, Coon, H, Han, Y, Stephens, S, Sun, J, Chen, X, Ducci, F, Dueker, N, Franceschini, N, Frank, J, Geller, F, Gubjartsson, D, Hansel, N, Jiang, C, Keskitalo-Vuokko, K, Liu, Z, Lyytikäinen, L, Michel, M, Rawal, R, Rosenberger, A
Formato: Journal article
Lenguaje:English
Publicado: 2012