One-pot catalytic enantioselective synthesis of 2-pyrazolines

A scalable, one-pot, enantioselective catalytic synthesis of 2-pyrazolines from beta-substituted enones and hydrazines is described. Pivoting on a two-stage catalytic Michael addition/condensation strategy, the use of an aldehyde to generate a suitable hydrazone derivative of the hydrazine was found...

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Bibliografiske detaljer
Main Authors: Thomson, C, Barber, D, Dixon, D
Format: Journal article
Sprog:English
Udgivet: Wiley 2019