Heterogeneous requirement of IkappaB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: implications for therapy.

OBJECTIVE: To investigate the potential role of IkappaB kinase 1 (IKK-1) and IKK-2 in the regulation of nuclear factor kappaB (NF-kappaB) activation and the expression of tumor necrosis factor alpha (TNFalpha), as well as interleukin-1beta (IL-1beta), IL-6, IL-8, vascular endothelial growth factor...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Andreakos, E, Smith, C, Kiriakidis, S, Monaco, C, de Martin, R, Brennan, F, Paleolog, E, Feldmann, M, Foxwell, B
Formatua: Journal article
Hizkuntza:English
Argitaratua: 2003