Clonal phylogenies inferred from bulk, single cell, and spatial transcriptomic analysis of epithelial cancers

Epithelial cancers are typically heterogeneous with primary prostate cancer being a typical example of histological and genomic variation. Prior studies of primary prostate cancer tumour genetics revealed extensive inter and intra-patient genomic tumour heterogeneity. Recent advances in machine lear...

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Detalhes bibliográficos
Principais autores: Erickson, A, Figiel, S, Rajakumar, T, Rao, S, Yin, W, Doultsinos, D, Magnussen, A, Singh, R, Poulose, N, Bryant, RJ, Cussenot, O, Hamdy, FC, Woodcock, D, Mills, IG, Lamb, AD
Formato: Journal article
Idioma:English
Publicado em: Public Library of Science 2025