CTCF regulates hepatitis B virus cccDNA chromatin topology

Hepatitis B Virus (HBV) is a small DNA virus that replicates via an episomal covalently closed circular DNA (cccDNA) that serves as the transcriptional template for viral mRNAs. The host protein, CCCTC-binding factor (CTCF), is a key regulator of cellular transcription by maintaining epigenetic boun...

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Bibliographic Details
Main Authors: Dobrica, MO, Varghese, CS, Harris, JM, Ferguson, J, Magri, A, Arnold, R, Várnai, C, Parish, JL, McKeating, JA
Format: Journal article
Language:English
Published: Microbiology Society 2024