Structure of the ultra-high-affinity colicin E2 DNase-Im2 complex
How proteins achieve high-affinity binding to a specific protein partner while simultaneously excluding all others is a major biological problem that has important implications for protein design. We report the crystal structure of the ultra-high-affinity protein-protein complex between the endonucl...
Main Authors: | Wojdyla, J, Fleishman, S, Baker, D, Kleanthous, C |
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Format: | Journal article |
Language: | English |
Published: |
2012
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