The CHEK2 variant C.349A>G is associated with prostate cancer risk and carriers share a common ancestor

The identification of recurrent founder variants in cancer predisposing genes may have important implications for implementing cost-effective targeted genetic screening strategies. In this study, we evaluated the prevalence and relative risk of the <i>CHEK2</i> recurrent...

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প্রধান লেখক: Brandão, A, Paulo, P, Maia, S, Pinheiro, M, Peixoto, A, Cardoso, M, Silva, MP, Santos, C, Eeles, RA, Kote-Jarai, Z, Muir, K, Ukgpcs Collaborators, Schleutker, J, Wang, Y, Pashayan, N, Batra, J, Apcb BioResource, Grönberg, H, Neal, DE, Nordestgaard, BG, Tangen, CM, Southey, MC, Wolk, A, Albanes, D, Haiman, CA, Travis, RC, Stanford, JL, Mucci, LA, West, CML, Nielsen, SF, Kibel, AS, Cussenot, O, Berndt, SI, Koutros, S, Sørensen, KD, Cybulski, C, Grindedal, EM, Park, JY, Ingles, SA, Maier, C, Hamilton, RJ, Rosenstein, BS, Vega, A, The Impact Study Steering Committee And Collaborators, Kogevinas, M, Wiklund, F, Penney, KL, Brenner, H, John, EM, Kaneva, R
বিন্যাস: Journal article
ভাষা:English
প্রকাশিত: MDPI 2020