Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution.

Virus-specific CD8+ T cell responses play an important role in the natural course of infection; however, the impact of certain CD8+ T cell responses in determining clinical outcome has not been fully defined. A well-defined cohort of women inoculated with HCV from a single source showed that HLA-B27...

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Bibliographic Details
Main Authors: Neumann-Haefelin, C, McKiernan, S, Ward, S, Viazov, S, Spangenberg, H, Killinger, T, Baumert, T, Nazarova, N, Sheridan, I, Pybus, O, von Weizsäcker, F, Roggendorf, M, Kelleher, D, Klenerman, P, Blum, H, Thimme, R
Format: Journal article
Language:English
Published: 2006