Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution.

Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution.

Virus-specific CD8+ T cell responses play an important role in the natural course of infection; however, the impact of certain CD8+ T cell responses in determining clinical outcome has not been fully defined. A well-defined cohort of women inoculated with HCV from a single source showed that HLA-B27...

Descrizione completa

Dettagli Bibliografici
Autori principali:	Neumann-Haefelin, C, McKiernan, S, Ward, S, Viazov, S, Spangenberg, H, Killinger, T, Baumert, T, Nazarova, N, Sheridan, I, Pybus, O, von Weizsäcker, F, Roggendorf, M, Kelleher, D, Klenerman, P, Blum, H, Thimme, R
Natura:	Journal article
Lingua:	English
Pubblicazione:	2006

Documenti analoghi

Dominant influence of an HLA-B27 restricted virus-specific CD8+T cell response in viral clearance and viral adaptation in hepatitis C virus infection
di: Neumann-Haefelin, C, et al.
Pubblicazione: (2005)

VIRAL FITNESS COST AND T CELL CROSS-RECOGNITION LIMIT VIRAL ESCAPE WITHIN A PROTECTIVE HLA-B27 RESTRICTED HEPATITIS C VIRUS SPECIFIC CD8+T CELL EPITOPE
di: Neumann-Haefelin, C, et al.
Pubblicazione: (2008)

Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response.
di: Dazert, E, et al.
Pubblicazione: (2009)

HCV-Specific T Cell Responses During and After Chronic HCV Infection
di: Hendrik Luxenburger, et al.
Pubblicazione: (2018-11-01)

Escape from HLA-B*08-restricted CD8 T cells by hepatitis C virus is associated with fitness costs.
di: Salloum, S, et al.
Pubblicazione: (2008)

RAPID AND EFFICIENT ANTIGEN PROCESSING AND PRESENTATION OF A PROTECTIVE AND IMMUNODOMINANT HLA-B*27-RESTRICTED HEPATITIS C VIRUS-SPECIFIC CD8+T CELL EPITOPE
di: Schmidt, J, et al.
Pubblicazione: (2012)

Analysis of the Evolutionary Forces in an Immunodominant CD8 Epitope in Hepatitis C Virus at a Population Level (vol 82, pg 3438, 2008)
di: Neumann-Haefelin, C, et al.
Pubblicazione: (2011)

Analysis of the evolutionary forces in an immunodominant CD8 epitope in hepatitis C virus at a population level
di: Neumann-Haefelin, C, et al.
Pubblicazione: (2011)

Analysis of the evolutionary forces in an immunodominant CD8 epitope in hepatitis C virus at a population level.
di: Neumann-Haefelin, C, et al.
Pubblicazione: (2008)

Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted hepatitis C virus-specific CD8+ T-cell epitope.
di: Schmidt, J, et al.
Pubblicazione: (2012)

Virus-specific CD4+ T cell responses in chronic HCV infection in blood and liver identified by antigen-specific upregulation of CD154.
di: Mueller, M, et al.
Pubblicazione: (2010)

Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope.
di: Neumann-Haefelin, C, et al.
Pubblicazione: (2010)

Natural history of hepatitis C
di: M Roggendorf, et al.
Pubblicazione: (2000-01-01)

PREDICTING CLEARANCE OF ACUTE HCV IN HIV-POSITIVE PATIENTS
di: Thomson, E, et al.
Pubblicazione: (2009)

Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted hepatitis C virus-specific CD8+ T-cell epitope.
di: Julia Schmidt, et al.
Pubblicazione: (2012-01-01)

Analysis of HCV in South East Asia
di: Barnes, E, et al.
Pubblicazione: (2007)

Methodologies for the analysis of HCV-specific CD4(+) T cells
di: Lokhande, M, et al.
Pubblicazione: (2015)

Longitudinal mapping of protective CD4+ T cell responses against HCV: analysis of fluctuating dominant and subdominant HLA-DR11 restricted epitopes.
di: Harcourt, G, et al.
Pubblicazione: (2004)

Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection.
di: Fitzmaurice, K, et al.
Pubblicazione: (2011)

Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection
di: Fitzmaurice, K, et al.
Pubblicazione: (2011)

Effect of HLA on hepatitis C virus clearance and persistence in anti-HCV-positive end-stage renal disease patients
di: Serkan Ocal, et al.
Pubblicazione: (2014-01-01)

Additive effects of HLA alleles and innate immune genes determine viral outcome in HCV infection.
di: Fitzmaurice, K, et al.
Pubblicazione: (2015)

Hepitopes: A live interactive database of HLA class I epitopes in hepatitis B virus
di: Lumley, S, et al.
Pubblicazione: (2016)

Methodologies for the analysis of HCV-specific CD4+ T cells
di: Megha eLokhande, et al.
Pubblicazione: (2015-02-01)

Protective effect of HLA-B57 on HCV genotype 2 infection in a West African population
di: Allain, J, et al.
Pubblicazione: (2006)

Protective effect of HLA-B57 on HCV genotype 2 infection in a West African population.
di: Chuang, W, et al.
Pubblicazione: (2007)

Hepatitis C Virus (HCV)–Apolipoprotein Interactions and Immune Evasion and Their Impact on HCV Vaccine Design
di: Florian Wrensch, et al.
Pubblicazione: (2018-06-01)

Adaptive Immune Responses, Immune Escape and Immune-Mediated Pathogenesis during HDV Infection
di: Valerie Oberhardt, et al.
Pubblicazione: (2022-01-01)

The generation of a simian adenoviral vectored HCV vaccine encoding genetically conserved gene segments to target multiple HCV genotypes
di: von Delft, A, et al.
Pubblicazione: (2017)

Ethnicity and Spontaneous Clearance of Hepatitis C in HIV-HCV Coinfected Patients
di: Lil Miedzinski, et al.
Pubblicazione: (2008-01-01)

Reversal of Immunity After Clearance of Chronic HCV Infection—All Reset?
di: Heiner Wedemeyer, et al.
Pubblicazione: (2020-10-01)

HCV-indeterminate blood donors or occult HCV infection? Reply
di: Semmo, N, et al.
Pubblicazione: (2005)

Immune Correlates of Natural HIV Elite Control and Simultaneous HCV Clearance—Supercontrollers
di: Beatriz Dominguez-Molina, et al.
Pubblicazione: (2018-12-01)

Historical evolution of strategic management /
di: McKiernan, Peter
Pubblicazione: (1996)

Invisible Hand(s): Quality Assurance in the Age of Author Self-Archiving
di: McKiernan Gerry
Pubblicazione: (2003-09-01)

Coordinated expansion of memory T follicular helper and B cells mediates spontaneous clearance of HCV reinfection
di: Mohamed Eisa, et al.
Pubblicazione: (2024-06-01)

Resistant-Associated Substitutions Do Not Affect HCV RNA and HCV Core Antigen Clearance During Direct-Acting Antiviral Agent Treatment in a Real-World Setting
di: Chen H, et al.
Pubblicazione: (2022-06-01)

HLA Footprints in HIV-1 Drive Phylogenetic Clustering and Inter-Clade Variation
di: Matthews, P, et al.
Pubblicazione: (2008)

Evidence for a Complex Mosaic Genome Pattern in a Full-length Hepatitis C Virus Sequence
di: R.S. Ross, et al.
Pubblicazione: (2008-01-01)

Evidence for a Complex Mosaic Genome Pattern in a Full-length Hepatitis C Virus Sequence
di: R.S. Ross, et al.
Pubblicazione: (2008-01-01)