Reprioritizing genetic associations in hit regions using LASSO-based resample model averaging.

Reprioritizing genetic associations in hit regions using LASSO-based resample model averaging.

Significance testing one SNP at a time has proven useful for identifying genomic regions that harbor variants affecting human disease. But after an initial genome scan has identified a "hit region" of association, single-locus approaches can falter. Local linkage disequilibrium (LD) can ma...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Valdar, W, Sabourin, J, Nobel, A, Holmes, C
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2012

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