Reprioritizing genetic associations in hit regions using LASSO-based resample model averaging.

Reprioritizing genetic associations in hit regions using LASSO-based resample model averaging.

Significance testing one SNP at a time has proven useful for identifying genomic regions that harbor variants affecting human disease. But after an initial genome scan has identified a "hit region" of association, single-locus approaches can falter. Local linkage disequilibrium (LD) can ma...

书目详细资料
Main Authors:	Valdar, W, Sabourin, J, Nobel, A, Holmes, C
格式:	Journal article
语言:	English
出版:	2012

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