The role of CD4+ T-cell subsets in determining transplantation rejection or tolerance.
Peripheral tolerance to allogeneic organ grafts can be induced in rodents by treating with non-depleting CD4 and CD8 monoclonal antibodies. This tolerance is maintained by CD4+ T cells with a potent capacity to induce tolerance in further cohorts of T cells (i.e. infectious tolerance). We have clone...
Autori principali: | Zelenika, D, Adams, E, Humm, S, Lin, C, Waldmann, H, Cobbold, S |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2001
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