The role of CD4+ T-cell subsets in determining transplantation rejection or tolerance.
Peripheral tolerance to allogeneic organ grafts can be induced in rodents by treating with non-depleting CD4 and CD8 monoclonal antibodies. This tolerance is maintained by CD4+ T cells with a potent capacity to induce tolerance in further cohorts of T cells (i.e. infectious tolerance). We have clone...
| Main Authors: | , , , , , |
|---|---|
| Format: | Journal article |
| Sprog: | English |
| Udgivet: |
2001
|