Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling.

<p><strong>Background:</strong> Observational studies suggest interconnections between thyroid status, metabolism, and risk of coronary artery disease (CAD), but causality remains to be proven. The present study aimed to investigate the potential causal relationship between thyroid...

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Những tác giả chính:	van Vliet, NA, Bos, MM, Thesing, CS, Chaker, L, Pietzner, M, Houtman, E, Neville, MJ, Li-Gao, R, Trompet, S, Mustafa, R, Ahmadizar, F, Beekman, M, Bot, M, Budde, K, Christodoulides, C, Dehghan, A, Delles, C, Elliott, P, Evangelou, M, Gao, H, Ghanbari, M, van Herwaarden, AE, Ikram, MA, Jaeger, M, Jukema, JW, Karaman, I, Karpe, F, Kloppenburg, M, Meessen, JMTA, Meulenbelt, I, Milaneschi, Y, Mooijaart, SP, Mook-Kanamori, DO, Netea, MG, Netea-Maier, RT, Peeters, RP, Penninx, BWJH, Sattar, N, Slagboom, PE, Suchiman, HED, Völzke, H, Willems van Dijk, K, Noordam, R, van Heemst, D
Tác giả khác:	BBMRI Metabolomics Consortium
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	BMC 2021

Higher thyrotropin leads to unfavorable lipid profile and somewhat higher cardiovascular disease risk: evidence from multi-cohort Mendelian randomization and metabolomic profiling.

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