What is the minimal length of calcium pentosan polysulfate that is able to block aggrecan breakdown in cartilage?

What is the minimal length of calcium pentosan polysulfate that is able to block aggrecan breakdown in cartilage?

Detalhes bibliográficos
Principais autores:	Troeberg, L, Mulloy, B, Nagase, H
Formato:	Journal article
Publicado em:	2009

Registros relacionados

Calcium pentosan polysulfate is a multi-functional aggrecanase inhibitor that enhances interaction with endogenous TIMP-3 in cartilage
por: Troeberg, L, et al.
Publicado em: (2009)

Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases.
por: Troeberg, L, et al.
Publicado em: (2008)

Calcium pentosan polysulfate increases affinity between aggrecanases (ADAMTS-4 and-5) and TIMP-3 by a conformational change
por: Troeberg, L, et al.
Publicado em: (2010)

Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex
por: Troeberg, L, et al.
Publicado em: (2012)

Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex.
por: Troeberg, L, et al.
Publicado em: (2012)

Aggrecan breakdown in cartilage induced by proteolytic fragments of fibronectin: implications in osteoarthritis
por: Nagase, H
Publicado em: (2009)

Pentosan Polysulfate Maculopathy—Prescribers Should Be Aware
por: Yusuf, IH, et al.
Publicado em: (2020)

Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate
por: Fuming Zhang, et al.
Publicado em: (2022-02-01)

Potentiation of carbon tetrachloride hepatotoxicity by pentosan polysulfate in rats
por: Zim M.C.A., et al.
Publicado em: (2002-01-01)

Pentosan Polysulfate Affords Pleotropic Protection to Multiple Cells and Tissues
por: Margaret M. Smith, et al.
Publicado em: (2023-03-01)

Use of Pentosan Polysulfate in the Local Treatment of Reactive Arthritis in Children
por: O.A. Danylov, et al.
Publicado em: (2016-05-01)

Type 3 macular neovascularization in a patient with pentosan polysulfate maculopathy
por: Elodie Bousquet, et al.
Publicado em: (2023-03-01)

Effectiveness of oral pentosan polysulfate in painful bladder syndrome: Is it worth the cost?
por: Devdatt Purushottam Palnitkar, et al.
Publicado em: (2021-01-01)

Maculopathy Secondary to Pentosan Polysulfate Use: A Single-Center Experience
por: Kalbag NS, et al.
Publicado em: (2021-02-01)

Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage.
por: Durigova, M, et al.
Publicado em: (2011)

Involvement of ADAMTS5 and hyaluronidase in aggrecan degradation and release from OSM-stimulated cartilage
por: M Durigova, et al.
Publicado em: (2011-01-01)

Advanced pentosan polysulfate sodium maculopathy with low cumulative exposure and hydroxychloroquine use
por: Elena Flester, et al.
Publicado em: (2024-12-01)

Acute and severe haemorrhage following pentosan polysulfate injection in a Cornish Rex
por: Miranda X Tong, et al.
Publicado em: (2021-11-01)

Pentosan Polysulfate Sodium-Associated Pigmentary Retinopathy: Risk Factors and Fundus Findings
por: Leung EH, et al.
Publicado em: (2021-12-01)

Efficacy of pentosan polysulfate in in vitro models of lysosomal storage disorders: Fabry and Gaucher Disease.
por: Andrea N Crivaro, et al.
Publicado em: (2019-01-01)

Isolation of fibronectin fragments that induce aggrecan degradation in cartilage
por: Sofat, N, et al.
Publicado em: (2006)

Fibronectin fragments induce aggrecan degradation in human cartilage and are increased in osteoarthritic cartilage
por: Sofat, N, et al.
Publicado em: (2007)

In-depth structural characterization of pentosan polysulfate sodium complex drug using orthogonal analytical tools
por: Alekseeva, Anna, et al.
Publicado em: (2021)

In-depth structural characterization of pentosan polysulfate sodium complex drug using orthogonal analytical tools
por: Alekseeva, Anna, et al.
Publicado em: (2022)

Retrospective study of incidence/prevalence of pigmentary maculopathy and retinopathy in patients receiving pentosan polysulfate sodium.
por: Zhong Yuan, et al.
Publicado em: (2025-01-01)

An unusual case of rapid resolution of bilateral vitelliform deposits after discontinuation of pentosan polysulfate sodium
por: Fritz Gerald P. Kalaw, et al.
Publicado em: (2023-12-01)

Xylan Prebiotics and the Gut Microbiome Promote Health and Wellbeing: Potential Novel Roles for Pentosan Polysulfate
por: Margaret M. Smith, et al.
Publicado em: (2022-09-01)

Screening practices and risk assessment for maculopathy in pentosan polysulfate users across different exposure levels
por: Hyeon Yoon Kwon, et al.
Publicado em: (2024-05-01)

JNK2 controls aggrecan degradation in murine articular cartilage and the development of experimental osteoarthritis.
por: Ismail, H, et al.
Publicado em: (2015)

Identifying synovial tissue-derived catabolic factors of cartilage aggrecan
por: Rana, F, et al.
Publicado em: (2013)

Apolipoprotein A-1 is a novel inducer of aggrecan breakdown in cultured articular cartilage
por: Didangelos, A, et al.
Publicado em: (2009)

Aggrecan structure in amphibian cartilage
por: Covizi D.Z., et al.
Publicado em: (2000-01-01)

Sentiments of Individuals with Interstitial Cystitis/Bladder Pain Syndrome Toward Pentosan Polysulfate Sodium: Infodemiology Study
por: Yulin Hswen, et al.
Publicado em: (2025-01-01)

Pigmentary Maculopathy in Interstitial Cystitis/Bladder Pain Syndrome Treated with Oral Pentosan Polysulfate: A Review
por: Richard Parkinson, et al.
Publicado em: (2022-09-01)

Inhibitory effects of sodium pentosan polysulfate on formation and function of osteoclasts derived from canine bone marrow
por: H. M. Suranji Wijekoon, et al.
Publicado em: (2018-05-01)

Probing nanomechanics of aggrecan and the aggrecan-rich pericellular matrix of chondrocytes in cartilage
por: Ng, Laurel Jean
Publicado em: (2006)

Transient Postoperative Hemorrhage from Elbow Arthroscopy Portals following Intra-Articular Pentosan Polysulfate Sodium Injection
por: Lindsay A. Parker, et al.
Publicado em: (2022-01-01)

Identification of Patients with Pentosan Polysulfate Sodium-Associated Maculopathy through Screening of the Electronic Medical Record at an Academic Center
por: Kendall Higgins, et al.
Publicado em: (2020-01-01)

The effect of pentosan polysulfate sodium for improving dyslipidaemia and knee pain in people with knee osteoarthritis: A pilot study
por: Xiaoqian Liu, et al.
Publicado em: (2023-06-01)

Role of oral pentosan polysulfate in Bacillus Calmette–Guérin therapy in patients with non-muscle-invasive bladder cancer
por: Ho Yeon Lee, et al.
Publicado em: (2022-09-01)