In situ analysis of LKB1/STK11 mRNA expression in human normal tissues and tumours.

The LKB1/STK11 serine/threonine kinase is mutated in Peutz-Jeghers' syndrome and acts as a tumour suppressor. Using northern blotting and RT-PCR, LKB1 has been reported to be expressed widely in human adult tissues, although in Xenopus the expression of its homologue, XEEK1, is apparently restr...

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Bibliographic Details
Main Authors: Rowan, A, Churchman, M, Jefferey, R, Hanby, A, Poulsom, R, Tomlinson, I
Format: Journal article
Language:English
Published: 2000