In situ analysis of LKB1/STK11 mRNA expression in human normal tissues and tumours.
The LKB1/STK11 serine/threonine kinase is mutated in Peutz-Jeghers' syndrome and acts as a tumour suppressor. Using northern blotting and RT-PCR, LKB1 has been reported to be expressed widely in human adult tissues, although in Xenopus the expression of its homologue, XEEK1, is apparently restr...
المؤلفون الرئيسيون: | , , , , , |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2000
|