In situ analysis of LKB1/STK11 mRNA expression in human normal tissues and tumours.
The LKB1/STK11 serine/threonine kinase is mutated in Peutz-Jeghers' syndrome and acts as a tumour suppressor. Using northern blotting and RT-PCR, LKB1 has been reported to be expressed widely in human adult tissues, although in Xenopus the expression of its homologue, XEEK1, is apparently restr...
المؤلفون الرئيسيون: | Rowan, A, Churchman, M, Jefferey, R, Hanby, A, Poulsom, R, Tomlinson, I |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2000
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مواد مشابهة
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Identification of a novel mRNA species of the LKB1/STK11 Peutz-Jeghers serine/threonine kinase.
حسب: Churchman, M, وآخرون
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Germline mutations of the LKB1 (STK11) gene in Peutz-Jeghers patients.
حسب: Wang, Z, وآخرون
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Further observations on LKB1/STK11 status and cancer risk in Peutz-Jeghers syndrome.
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منشور في: (2003) -
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منشور في: (2017) -
Tumor loss-of-function mutations in STK11/LKB1 induce cachexia
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منشور في: (2023-04-01)