Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide.

An experimentally simple protocol for the very highly (E)-selective Wadsworth-Emmons reaction [(E):(Z) selectivities in excess of 180:1 in some cases] of a range of straight-chain and branched aliphatic, substituted aromatic, and base-sensitive aldehydes via reaction with an alkyl diethylphosphonoac...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Claridge, T, Davies, S, Lee, J, Nicholson, R, Roberts, P, Russell, A, Smith, A, Toms, S
Format: Journal article
Sprache:English
Veröffentlicht: 2008