Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide.
An experimentally simple protocol for the very highly (E)-selective Wadsworth-Emmons reaction [(E):(Z) selectivities in excess of 180:1 in some cases] of a range of straight-chain and branched aliphatic, substituted aromatic, and base-sensitive aldehydes via reaction with an alkyl diethylphosphonoac...
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Bibliographic Details
Main Authors: |
Claridge, T,
Davies, S,
Lee, J,
Nicholson, R,
Roberts, P,
Russell, A,
Smith, A,
Toms, S |
Format: | Journal article
|
Language: | English |
Published: |
2008
|