Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide.

An experimentally simple protocol for the very highly (E)-selective Wadsworth-Emmons reaction [(E):(Z) selectivities in excess of 180:1 in some cases] of a range of straight-chain and branched aliphatic, substituted aromatic, and base-sensitive aldehydes via reaction with an alkyl diethylphosphonoac...

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Main Authors: Claridge, T, Davies, S, Lee, J, Nicholson, R, Roberts, P, Russell, A, Smith, A, Toms, S
Format: Journal article
Language:English
Published: 2008
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author Claridge, T
Davies, S
Lee, J
Nicholson, R
Roberts, P
Russell, A
Smith, A
Toms, S
author_facet Claridge, T
Davies, S
Lee, J
Nicholson, R
Roberts, P
Russell, A
Smith, A
Toms, S
author_sort Claridge, T
collection OXFORD
description An experimentally simple protocol for the very highly (E)-selective Wadsworth-Emmons reaction [(E):(Z) selectivities in excess of 180:1 in some cases] of a range of straight-chain and branched aliphatic, substituted aromatic, and base-sensitive aldehydes via reaction with an alkyl diethylphosphonoacetate and MeMgBr is reported.
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spelling oxford-uuid:d67dfa1f-28be-497e-b32c-d974b27d22d42022-03-27T08:33:53ZHighly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:d67dfa1f-28be-497e-b32c-d974b27d22d4EnglishSymplectic Elements at Oxford2008Claridge, TDavies, SLee, JNicholson, RRoberts, PRussell, ASmith, AToms, SAn experimentally simple protocol for the very highly (E)-selective Wadsworth-Emmons reaction [(E):(Z) selectivities in excess of 180:1 in some cases] of a range of straight-chain and branched aliphatic, substituted aromatic, and base-sensitive aldehydes via reaction with an alkyl diethylphosphonoacetate and MeMgBr is reported.
spellingShingle Claridge, T
Davies, S
Lee, J
Nicholson, R
Roberts, P
Russell, A
Smith, A
Toms, S
Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide.
title Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide.
title_full Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide.
title_fullStr Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide.
title_full_unstemmed Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide.
title_short Highly (E)-selective Wadsworth-Emmons reactions promoted by methylmagnesium bromide.
title_sort highly e selective wadsworth emmons reactions promoted by methylmagnesium bromide
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AT leej highlyeselectivewadsworthemmonsreactionspromotedbymethylmagnesiumbromide
AT nicholsonr highlyeselectivewadsworthemmonsreactionspromotedbymethylmagnesiumbromide
AT robertsp highlyeselectivewadsworthemmonsreactionspromotedbymethylmagnesiumbromide
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