Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans.

Type I interferon (IFN) is crucial during infection through its antiviral properties and by coordinating the immunocompetent cells involved in antiviral or antibacterial immunity. Type I IFN (IFN-α and IFN-β) is produced after virus or bacteria recognition by cytosolic receptors or membrane-bound TL...

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Bibliographic Details
Main Authors: del Fresno, C, Soulat, D, Roth, S, Blazek, K, Udalova, I, Sancho, D, Ruland, J, Ardavín, C
Format: Journal article
Language:English
Published: 2013