Elongation/termination factor exchange mediated by PP1 phosphatase orchestrates transcription termination

Termination of RNA polymerase II (Pol II) transcription is a key step that is important for 3′ end formation of functional mRNA, mRNA release, and Pol II recycling. Even so, the underlying termination mechanism is not yet understood. Here, we demonstrate that the conserved and essential termination...

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Main Authors: Kecman, T, Kuś, K, Heo, D, Duckett, K, Birot, A, Liberatori, S, Mohammed, S, Geis-Asteggiante, L, Robinson, C, Vasiljeva, L
格式: Journal article
语言:English
出版: Cell Press 2018