The cortical actin network regulates avidity-dependent binding of hyaluronan by the Lymphatic Vessel Endothelial receptor LYVE-1

Lymphatic vessel endothelial hyaluronan receptor 1 (LYVE-1) mediates the docking and entry of dendritic cells to lymphatic vessels through selective adhesion to its ligand hyaluronan in the leucocyte surface glycocalyx. To bind hyaluronan efficiently, LYVE-1 must undergo surface clustering, a proces...

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Bibliographic Details
Main Authors: Stanly, TA, Fritzsche, M, Banerji, S, Shrestha, D, Schneider, F, Eggeling, C, Jackson, DG
Format: Journal article
Language:English
Published: American Society for Biochemistry and Molecular Biology 2020