Susceptibility to multiple sclerosis is associated with the proximal immunoglobulin heavy chain variable region.
15 immunoglobulin heavy chain constant (CH) and variable region (VH) polymorphisms were selected to span the entire length of the heavy chain cluster. These polymorphisms were examined in 34 sib pairs concordant for multiple sclerosis (MS) and in 23 sporadic MS patients. Allele frequencies were calc...
| Main Authors: | , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1991
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