Endothelin-1 increases superoxide production in human coronary artery bypass grafts

Aims: Endothelin-1 (ET-1) has been shown to increase endothelial superoxide (O2-) production in experimental animal models. It is unclear whether ET-1 increases O2- production in humans. We sought to elucidate whether ET-1 increases O2- production in human vessels and to identify the mechanism behin...

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Bibliographic Details
Main Authors: Cerrato, R, Cunnington, C, Crabtree, M, Antoniades, C, Pernow, J, Channon, K, Bohm, F
Format: Journal article
Language:English
Published: 2012