Mapping CD55 function. The structure of two pathogen-binding domains at 1.7 A.

Decay-accelerating factor (CD55), a regulator of the alternative and classical pathways of complement activation, is expressed on all serum-exposed cells. It is used by pathogens, including many enteroviruses and uropathogenic Escherichia coli, as a receptor prior to infection. We describe the x-ray...

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Bibliographic Details
Main Authors: Williams, P, Chaudhry, Y, Goodfellow, I, Billington, J, Powell, R, Spiller, O, Evans, D, Lea, S
Format: Journal article
Language:English
Published: 2003