Mapping CD55 function. The structure of two pathogen-binding domains at 1.7 A.
Decay-accelerating factor (CD55), a regulator of the alternative and classical pathways of complement activation, is expressed on all serum-exposed cells. It is used by pathogens, including many enteroviruses and uropathogenic Escherichia coli, as a receptor prior to infection. We describe the x-ray...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2003
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