IgA and IgG1 specific to vi polysaccharide of salmonella typhi correlate with protection status in a typhoid fever controlled human infection model

Vaccination against Salmonella Typhi using the Vi capsular polysaccharide, a T-cell independent antigen, can protect from the development of typhoid fever. This implies that antibodies to Vi alone can protect in the absence of a T cell-mediated immune response; however, protective Vi antibodies have...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Dahora, L, Jin, C, Spreng, R, Feely, F, Mathura, R, Seaton, K, Zhang, L, Hill, J, Jones, E, Alam, S, Dennison, S, Pollard, A, Tomaras, G
פורמט: Journal article
שפה:English
יצא לאור: Frontiers Media 2019