Achieving a good crystal system for crystallographic X-ray fragment screening
The XChem facility at Diamond Light Source offers fragment screening by X-ray crystallography as a general access user program. The main advantage of X-ray crystallography as a primary fragment screen is that it yields directly the location and pose of the fragment hits, whether within pockets of in...
| Main Authors: | , , , , , , |
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| Format: | Book section |
| Published: |
Elsevier
2018
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