Achieving a good crystal system for crystallographic X-ray fragment screening

The XChem facility at Diamond Light Source offers fragment screening by X-ray crystallography as a general access user program. The main advantage of X-ray crystallography as a primary fragment screen is that it yields directly the location and pose of the fragment hits, whether within pockets of in...

Повний опис

Бібліографічні деталі
Автори: Collins, P, Douangamath, A, Talon, R, Dias, A, Brandão-Neto, J, Krojer, T, Von Delft, F
Формат: Book section
Опубліковано: Elsevier 2018