Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis.

INTRODUCTION: Despite the advent of biological therapies for the treatment of rheumatoid arthritis, there is a compelling need to develop alternative therapeutic targets for nonresponders to existing treatments. Soluble receptors occur naturally in vivo, such as the splice variant of the cell surfa...

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Bibliographic Details
Main Authors: Jin, P, Zhang, J, Sumariwalla, P, Ni, I, Jorgensen, B, Crawford, D, Phillips, S, Feldmann, M, Shepard, H, Paleolog, E
Format: Journal article
Language:English
Published: BioMed Central 2008