Updating the RNA polymerase CTD code: adding gene-specific layers.

The carboxyl-terminal domain (CTD) of RNA polymerase (pol) II comprises multiple tandem repeats with the consensus sequence Tyr(1)-Ser(2)-Pro(3)-Thr(4)-Ser(5)-Pro(6)-Ser(7) that can be extensively and reversibly modified in vivo. CTD modifications orchestrate the interplay between transcription and...

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Bibliographic Details
Main Authors: Egloff, S, Dienstbier, M, Murphy, S
Format: Journal article
Language:English
Published: 2012