Updating the RNA polymerase CTD code: adding gene-specific layers.
The carboxyl-terminal domain (CTD) of RNA polymerase (pol) II comprises multiple tandem repeats with the consensus sequence Tyr(1)-Ser(2)-Pro(3)-Thr(4)-Ser(5)-Pro(6)-Ser(7) that can be extensively and reversibly modified in vivo. CTD modifications orchestrate the interplay between transcription and...
Main Authors: | , , |
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Format: | Journal article |
Language: | English |
Published: |
2012
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