Haplotype-specific expression of the N-terminal exons 2 and 3 at the human MAPT locus.

The microtubule-associated protein tau (MAPT) H1 haplotype shows a strong association to the sporadic neurodegenerative diseases, progressive supranuclear palsy and corticobasal degeneration. The functional biological mechanisms behind the genetic association have started to emerge with differences...

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Detalhes bibliográficos
Principais autores: Caffrey, T, Joachim, C, Wade-Martins, R
Formato: Journal article
Idioma:English
Publicado em: 2008