KATP channel activation induces ischemic preconditioning of the endothelium in humans in vivo.

BACKGROUND: Endothelial dysfunction contributes to ischemia-reperfusion injury (IRI) and is reduced by ischemic preconditioning (IPC). IPC may involve activation of ATP-sensitive potassium channels (K(ATP)). We determined whether modulation of K(ATP) channels occurs in endothelial IPC in humans. MET...

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Bibliographic Details
Main Authors: Broadhead, M, Kharbanda, R, Peters, M, MacAllister, R
Format: Journal article
Language:English
Published: 2004