Longitudinal changes in DNA methylation associated with clozapine use in treatment-resistant schizophrenia from two international cohorts

The second-generation antipsychotic clozapine is used as a medication for treatment-resistant schizophrenia. It has previously been associated with epigenetic changes in pre-clinical rodent models and cross-sectional studies of treatment-resistant schizophrenia. Cross-sectional studies are susceptib...

Full description

Bibliographic Details
Main Authors: Gillespie, AL, Walker, EM, Hannon, E, McQueen, GA, Sendt, K, Avila, A, Lally, J, Okhuijsen-Pfeifer, C, van der Horst, M, Hasan, A, Dempster, EL, Burrage, J, Bogers, J, Cohen, D, Boks, MP, Collier, DA, Egerton, A, Luykx, JJ, Mill, J, MacCabe, JH
Format: Journal article
Language:English
Published: Springer Nature [academic journals on nature.com] 2024