The functional consequences of autoimmune variants in the tyrosine kinase 2 gene region

<p>The tyrosine kinase 2 (TYK2) gene was first implicated in autoimmune disease in 2009 when a nonsynonymous single nucleotide polymorphism (nsSNP) in <em>TYK2</em> was reported to be associated with multiple sclerosis (MS). The immunological function of TYK2, as a kinase involved...

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Bibliographic Details
Main Author: Shipman, L
Other Authors: Fugger, L
Format: Thesis
Language:English
Published: 2014
Subjects: