Astrocyte-secreted glypican 4 regulates release of neuronal pentraxin 1 from axons to induce functional synapse formation

The generation of precise synaptic connections between developing neurons is critical to the formation of functional neural circuits. Astrocyte-secreted glypican 4 induces formation of active excitatory synapses by recruiting AMPA glutamate receptors to the postsynaptic cell surface. We now identify...

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Bibliographic Details
Main Authors: Farhy-Tselnicker, I, Van Casteren, A, Lee, A, Chang, V, Aricescu, A, Allen, N
Format: Journal article
Language:English
Published: Elsevier 2017