Astrocyte-secreted glypican 4 regulates release of neuronal pentraxin 1 from axons to induce functional synapse formation
The generation of precise synaptic connections between developing neurons is critical to the formation of functional neural circuits. Astrocyte-secreted glypican 4 induces formation of active excitatory synapses by recruiting AMPA glutamate receptors to the postsynaptic cell surface. We now identify...
Main Authors: | Farhy-Tselnicker, I, Van Casteren, A, Lee, A, Chang, V, Aricescu, A, Allen, N |
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Format: | Journal article |
Language: | English |
Published: |
Elsevier
2017
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