Different pathways of human T-cell activation revealed by PHA-P and PHA-M.

Different pathways of human T-cell activation revealed by PHA-P and PHA-M.

Antigen-specific T-cell activation is mediated via the CD3-Ti (antigen receptor) complex, and monoclonal antibodies to both CD3 and Ti cause a rapid rise in intracellular Ca2+. This calcium mobilization is not inhibited by monoclonal antibodies to CD2. The rise in calcium mobilization induced by pur...

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Bibliografiske detaljer
Main Authors:	O'Flynn, K, Russul-Saib, M, Ando, I, Wallace, D, Beverley, P, Boylston, A, Linch, D
Format:	Journal article
Sprog:	English
Udgivet:	1986

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